Glossary

 Common Terms for LMS

 

Adjuvant Chemotherapy – Having chemo when you are NED
AI – Aromatase inhibitor is a drug that blocks estrogen from being made post menopause      
AIM – Chemo combination of Adriamyacin/Ifosfamide/mesna. Adriamyacin is now known as doxorubicin
Angiogenesis – Growth of new blood vessels. Anti-angiogenesis is prevention of growth of new blood vessels
Anti-PD-1 and PD-L1 – immune check point blockade inhibitors (immunotherapy)
BSO – Bilateral salpho-oopherectomy is surgical removal of both ovaries
Cancer Vaccine –
 vaccine to prevent or eliminate cancer using the body’s own immune system (immunotherapy) 
CD47 – a cell protein which is expressed in most LMS tumors and many other cells in the body   
CR – Complete response or remission
CT scan
 – Computerized Tomography scan sometimes refered to as a CAT scan
DFCI – Dana Farber Cancer Institute in Boston
Dx – Diagnosis
Er/Pr – Estrogen receptor/progesterone receptor.  If the tumor has these receptors then it is hormone sensitive leading to tumor growth.
Gem/Tax – Chemo combination of Gemcitabine and Taxotere                                                 Immunotherapy – Using your own body’s immune system to recognise and kill your cancer cells
LMS – short for the big word – Leiomyosarcoma
Macrophage – an immune system cell that can destroy/remove foreign molecules in the body (good) or stimulate tumor growth (bad)
MDA – MD Anderson Cancer Center in Huston, TX
MET – short for metastasis (a tumor found outside the original site)
MI – mitotic index
Morcellation –  the cutting or shredding of the uterus during hysterectomy
MSKCC – Memorial Sloan Kettering Cancer Center (New York)
NED – No Evidence of Disease. Refers to whether or not any tumors were found on your CT scan. You can still have cancer cells, but they are not large enough to be found on your scans.
Onc – Oncologist
OS – Overall Survival
PD – Progressive disease
PET scan – Positron emission tomography. A procedure similar to CT scan but using a small amount of glucose (sugar) injected into the vein. Because cancer cells often use more glucose than normal cells, the pictures in a PET scan can be used to find cancer
RFA – Radio Frequency Ablation
RLMS – Retroperitonel LMS
Sarcoma – cancers of the connective tissues: bone, muscle, fat, ligament.  There are over 60 different types, all not related to each other  genectically
Smooth muscles – the involuntary muscles such as blood vessels, uterus and peritoneum.  LMS is a cancer of the smooth muscles which are soft tissue sarcomas
STS – Soft tissue sarcoma versus sarcoma of the bone
TAH – Total abdominal hysterectomy
ULMS – Uterine Leiomyosarcoma
VATS – Video Assisted Thoracic Surgery
VEGF – Vascular endothelial growth factor which is commonly expressed in LMS cells

Also see:

List of Common Drugs for LMS

NCINational Cancer Institute’s Dictionary of Cancer Terms